By Graham Hughes, Shirish Sangle, Simon Bowman
Sjögren’s syndrome is now thought of pivotal within the spectrum of auto-immune problems. It provides in a number of guises, together with fatigue, aches and pains, nutrition and different bronchial asthma and never strangely is usually misdiagnosed as, for instance, ‘fibromyalgia, ‘M.E.’, glandular fever and so on. It additionally usually overlaps with different auto-immune stipulations resembling hypothyroidism (Hashimotos), Hughes Syndrome and coeliac affliction. analysis is mainly very important because it frequently responds to remedy, particularly with quinine derivatives (Plaquenil).
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Sjögren’s syndrome is now thought of pivotal within the spectrum of auto-immune issues. It offers in various guises, together with fatigue, aches and pains, meals and different bronchial asthma and never strangely is often misdiagnosed as, for instance, ‘fibromyalgia, ‘M. E. ’, glandular fever and so on. It additionally often overlaps with different auto-immune stipulations corresponding to hypothyroidism (Hashimotos), Hughes Syndrome and coeliac ailment.
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Additional info for Sjögren’s Syndrome in Clinical Practice
They never turned out to be malignant, but nevertheless, caused considerable anxiety. G. 1007/978-3-319-06059-0_7, © Springer International Publishing Switzerland 2014 31 32 Chapter 7. Bladder, Vagina, Kidney Our theory for this finding is that the abnormal cervical smear reflects the abnormal dry local environment in the vagina in some of these patients. Kidney The dryness in the bladder fortunately doesn’t appear to result in an increased risk of kidney infections. However, the kidney can occasionally, be directly involved in Sjögrens – a figure usually put at around 5 %, though we believe the figure to be lower.
However, some of the diseases often associated with Sjögren’s syndrome, can and do cause bowel symptoms – some of these are listed: Coeliac Disease Coeliac disease, another of the auto-immune disorders, is associated with Sjögren’s syndrome. The condition is known to be due to sensitivity to gluten – a constituent of wheat products. : in children before the cause became recognised), the flatulence, abdominal pain, diarrhoea and malabsorption, often lead to severe weight loss and vitamin deficiencies.
A rare association with Sjögren’s it should be said). A more modest form of ‘low-grade’ myositis with muscle aches, a moderately raised CPK and minor changes in the EMG is sometimes seen. 42 Chapter 9. 3 Magnetic resonance imaging showing myositis in a patient with Sjögren’s syndrome (bright signal indicates muscle inflammation) Chapter 10 Sjögren’s and Lymphoma Introduction There is an increased incidence of lymphoma in Sjögrens. While this is often the first thing a patient reads on an internet search, there are important figures and facts to note.