By L. G. Lajtha, E. G. Wright (auth.), Siegmund J. Baum, G. David Ledney (eds.)
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Extra info for Experimental Hematology Today 1978
001. 0 colonies. Thus, rescue was not effected by heparin. after appropriate absorption are similar to those reported by other investigators (12,13,14,15,24,28); thus, we can assume that we are dealing with a very similar antiserum. In these studies, we have shown that carrageenan treatment of mice can rescue the spleen colony-forming capacity of RAMBS-r-treated CFU-s. By exploiting this observation and the observations of others on the activities of the carrageenans, we may be able to shed some light on the mechanism of RAMBS anti-CFU-s activity.
13. S. Brain-associated () antigen: Reactivity of rabbit anti-mouse brain with mouse lymphoid cells. Cell. , 2:353, 1971. 31 Regulation of Stem Cell Proliferation 14. S. Brain-associated stem cell antigen: An antigen shared by brain and hemopoietic cells. J. Exp. , 136:369, 1972. 15. S. Brain-associated erythrocyte antigen: An antigen shared by brain and erythrocytes. Exp. , 1: 105, 1973. 16. G. Antipeptic and antithrombotic properties of carrageenan. J. Lab. CUn. , 60:641, 1%2. 17. G. The antithrombotic activity of carrageenan in human blood.
Separation studies are warranted to examine this phenomena further. 2-positive cells in vitro, and the WIWv bone marrow has sufficient numbers of stem cells to protect a lethally irradiated mouse (10), it was felt that perhaps thymosin might induce the formation of TSRC, which, in tum, could generate normal stem cell proliferation from WIWv bone marrow. The result of incubation of WIWV bone marrow with thymosin (a) to generate sufficient colonies in +1+ mice and (b) to prevent WIWv anemia, met with complete failure (Figures 3-1 and 3-2).