By Carolina Witchmichen Penteado Schmidt, Fabiana Gatti de Menezes
There are few courses approximately drug interactions in chemotherapy or even much less approximately pediatric oncology remedy. as a result, the current booklet is meant to supply directions approximately drug interactions for physicians, pharmacists and the opposite healthcare pros enthusiastic about the chemotherapy of pediatric sufferers. during this publication the reader may have entry to a prime advent for the foremost ailments in pediatric oncology, through the key healing protocols. Following that, crucial drug interactions in pediatric oncology therapy are awarded and mentioned intimately. eventually, vital themes similar to Drug-Food Interactions are addressed. Drug treatment and Interactions in Pediatric Oncology focuses in nice aspect at the drug interactions in Pediatric Oncohematology and should be an essential source in day-by-day perform for a variety of healthiness providers.
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Additional info for Drug Therapy and Interactions in Pediatric Oncology: A Pocket Guide
In Brazil, there are health policies focused on basic child care, such as breastfeeding, child protection from violence, and children’s nutrition; Brazil is considered to be a country in development, and child health policy is focused on diseases such as malnutrition and health problems arising from poor sanitation . The diagnosis and treatment of cancer represent a significant proportion of the investments in health care around the world . In Latin America, the cure rate for childhood cancer remains considerably lower than that in developed countries, despite some progress.
The treatment in childhood usually consists of a combination of chemotherapy and low-dose radiotherapy. In this combined modality treatment, survival is achieved in up to 90 % . 2 Non-Hodgkin Lymphoma (NHL) Non-Hodgkin lymphoma is a group of diseases that comprise the Burkitt, large-cell, and lymphoblastic subtypes, as classified according to the World Health Organization system. Lymphoblastic lymphoma represents approximately 30 % of all pediatric NHL cases and the vast majority consists of advanced-stage lymphoblastic lymphoma with a precursor T-cell immunophenotype .
33 Source: Based on information from Valsecchi et al. 11 Source: Based on information from Valsecchi et al.  24 Chapter 1. 7 Childhood Cancer in Oceania In Oceania, the risk of Burkitt’s lymphoma is highest in Papua New Guinea, due to the association of this lymphoma with infection by the Epstein-Barr virus and the intense stimulation of immunity caused by malaria. In children who have immunodeficiency, the Epstein-Barr virus is probably also implicated in Hodgkin disease, non-Hodgkin lymphomas, nasopharyngeal carcinoma, and other cancers [72, 73].