By Harry H S Fong, Ping-Chung Leung, Charlie Changli Xue
The second one quantity of this publication sequence at the sleek perform of chinese language drugs keeps with the point of interest on evidence-based TCM study. it really is fascinated with special information regarding the simplest resources of natural offer and its quality controls required for examine and drug improvement reasons. natural caliber has consistently been a tremendous main issue for TCM researchers since it is hard to understand that is of the very best quality. another well known subject matters also are entertained.
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Extra info for Current Review of Chinese Medicine: Quality Control of Herbs And Herbal Material (Annals of Traditional Chinese Medicine)
Our advocacy of this requirement has recently been validated the World Health Organization Programme on Traditional Medicine (WHO/TRM) through its publication (WHO, 2003) of a guideline on good agriculture and collection practices (GACP) for the acquisition of quality botanicals for research, and by the National Center for Complementary and Alternative Medicine (NCCAM), NIH (USA), which established an interim guidance on product quality for grant applicants (2005). In spite of our philosophy and prior experiences in acquiring medicinal plants for our drug discovery research, we nevertheless encountered some challenging problems in the procurement of quality source materials for our botanical supplements/herbal medicine research.
C. Leung While the draft recommendations might appear quite comprehensive, explanations might still be deficient. A better conceptual account could be obtained from the World Health Organization, which obviously has made use of the Chinese Recommendations as the backbone of its own document concerning GAP. A summary of the WHO document is supplied below. 1 Background Some reported adverse events following the use of certain herbal medicines have been associated with a variety of possible explanations, including the inadvertent use of the wrong plant species, adulteration with undeclared other medicines and/or potent substances, contamination with undeclared toxic and/or hazardous substances, over-dosage, inappropriate use by health care providers or consumers, and interaction with other medicines, resulting in an adverse drug interaction.
Et al. (2003) Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. J. Agric. Food Chem. 51, 5661-5670. , et al. (2002) Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. J. Nutr. 132, 27-30. , et al. (2002) Isolation, structure elucidation and absolute configuration of 26 deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. J. Nat. Prod. 65, 601-605.