By Harald Theml
A Flexibook for either the expert and non-specialist, the new e-book bargains obtainable details on hematology in a succinct structure. as well as supplying simple technique, the booklet makes use of greater than 260 colour illustrations to element the main up to date scientific techniques. a variety of tables and circulate charts are incorporated to aid in differential prognosis, making this a worthwhile didactic reference for nurses, training physicians and citizens getting ready for board examinations.
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Additional resources for Color Atlas of Hematology
4. After careful consideration of the results obtained so far and the patient's clinical record, the last step is the analysis of the cell composition of the bone marrow. Quite often, suspected diagnoses are confirmed through humoral tests such as electrophoresis, or through cytochemical tests such as alkaline phosphatase, myeloperoxidase, nonspecific esterase, esterase, or iron tests. Bone marrow analysis is indicated when clinical findings and blood analysis leave doubts in the diagnostic assessment, for example in cases of: ➤ Leukocytopenia ➤ Thrombocytopenia ➤ Undefined anemia ➤ Tricytopenia, or ➤ Monoclonal hypergammaglobulinemia A bone marrow analysis may be indicated in order to evaluate the spreading of a lymphadenoma or tumor, unless the bloodstream already shows the presence of pathological cells.
35) and thus to be assigned to the erythrocyte series. After mitosis, their daughter cells display similar characteristics except that they have smaller nuclei. Daughter cells are called basophilic erythroblasts (formerly also called macroblasts). Their nuclei are smaller and the chromatin is more coarsely structured. The maturation of cells in the erythrocyte series is closely linked to the activity of macrophages (transformed monocytes), which phagocytose nuclei expelled from normoblasts and iron from senescent erythrocytes, and pass these cell components on to developing erythrocytes.
Nucleoli are rarely seen. The cytoplasm wraps quite closely around the nucleus and is slightly basophilic. Only a few lymphocytes display the violet stained stippling of granules; about 5% of small lymphocytes and about 3% of large ones. The family of large lymphocytes with granulation consists mostly of NK cells. An important point is that small lymphocytes—which cannot be identified as T- or B-lymphocytes on the basis of morphology—are not functional end forms, but undergo transformation in response to specific immunological stimuli.