By Barbara J. Bain
- allows either the haematologist and laboratory scientist to spot blood mobile positive aspects, from the most typical to the extra obscure
- presents crucial info on equipment of assortment, blood movie education and marking, including the foundations of handbook and automatic blood counts
- thoroughly revised and up-to-date, incorporating a lot newly released info: now comprises suggestion on extra exams while a selected analysis is suspected
- four hundred prime quality photos to help with blood mobilephone identification
- Highlights the aim and scientific relevance of haematology laboratory exams all through
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Additional info for Blood Cells A Practical Guide, 5 edition
This deinition is also accepted by the ICSH . (a) (b) Fig. 4 Reticulocytes stained with new methylene blue. (a) A group I reticulocyte with a dense clump of reticulum, several group II reticulocytes with a wreath or network of reticulum and several group III reticulocytes with a disintegrated wreath of reticulum. (b) Group II, III and IV reticulocytes: the group IV reticulocyte has two granules of reticulum. There is also a cell with a single dot of reticulum. By some criteria this would also be classiied as a reticulocyte.
This procedure and the use of an absolute reticulocyte count give similar information. A more complex correction  can be made that allows for the fact that in anaemic persons, under the inluence of an increased concentration of erythropoietin, reticulocytes are released prematurely from the bone marrow and spend longer in the blood before becoming mature red cells. The reticulocyte index and the absolute reticulocyte count both give a somewhat false impression of bone marrow output in this circumstance.
Results should be lagged: (i) when the blood sample contains blast cells, granulocyte precursors (often referred to as immature granulocytes), NRBC or atypical lymphocytes; (ii) when there are giant or aggregated platelets or for any reason red cell and platelet populations cannot be separated; and (iii) when there is an abnormality likely to be associated with factitious results. A new challenge to automated instruments is the production of accurate red cell indices, as well as total haemoglobin concentration, in patients who are infused with haemoglobin‐based blood substitutes.